Which studies are performed in the workup of gastric cancer?

Updated: Feb 23, 2021
  • Author: Elwyn C Cabebe, MD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Studies for staging of stomach cancer may include the following [4] :

  • Upper gastrointestinal (GI) tract endoscopy and biopsy
  • Chest/abdomen/pelvic computed tomography (CT) with oral and intravenous contrast
  • Positron emission tomography (PET) – CT evaluation if no evidence of M1 disease is found, and if clinically indicated
  • Complete blood cell count (CBC) and comprehensive chemistry profile
  • Endoscopic ultrasound if no evidence of M1 disease is found
  • Endoscopic resection for early-stage cancers
  • Biopsy of metastatic disease as clinically indicated
  • Microsatellite instability (MSI) and deficient mismatch repair (dMMR) testing if metastatic disease is documented/suspected
  • HER2-neu and programmed death ligand 1 (PD-L1) testing if metastatic adenocarcinoma is documented or suspected

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