How is follicular thyroid cancer (FTC) staged?

Updated: Jun 18, 2020
  • Author: Luigi Santacroce, MD; Chief Editor: Neetu Radhakrishnan, MD  more...
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Answer

The accurate assessment of the proliferative grading and the extent of invasion have high prognostic value and are mandatory in every specimen.

The accurate assessment of the proliferative grade and the extent of invasion have high prognostic value and are mandatory in every specimen.

The staging of well-differentiated thyroid cancers is related to age for the first and second stages but not for the third and fourth stages.

In patients younger than 45 years, staging is as follows:

  • Stage I: Any T, any N, M0 (Cancer is in the thyroid only.)

  • Stage II: Any T, any N, M1 (Cancer has spread to distant organs.)

In patients older than 45 years, staging is as follows:

  • Stage I: T1, N0, M0 (Cancer is in the thyroid only, in one or both lobes.)

  • Stage II: T2, N0, M0 and T3, N0, M0 (Cancer is in the thyroid only and is larger than 1.5 cm.)

  • Stage III: T4, N0, M0 and any T, N1, M0 (Cancer has spread outside the thyroid but not outside of the neck.)

  • Stage IV: Any T, any N, M1 (Cancer has spread to other parts of the body.)

See Thyroid Cancer Staging for more information.


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