What are the NCCN guidelines for colon cancer screening in patients at increased risk?

Updated: Apr 15, 2020
  • Author: Tomislav Dragovich, MD, PhD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Answer

The NCCN guidelines provide screening recommendations for patients at increased risk due to any of the following [155] :

  • Personal history of adenoma or sessile serrated polyp
  • Personal history of colorectal cancer
  • Inflammatory bowel disease
  • Positive family history

The guidelines also specify recommendations for patients with the following high-risk syndromes [156] :

  • Lynch syndrome

  • Familial adenomatous polyposis (FAP)

  • Attenuated familial adenomatous polyposis (AFAP)

  • MUTHYH-associated polyposis

  • Peutz-Jeghers syndrome (PJS)

  • Juvenile polyposis syndrome (JPS)

  • Serrated polyposis syndrome (SPS)

  • No syndrome, but familial risk present


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