Which biologic agents are used to treat colon cancer?

Updated: Apr 15, 2020
  • Author: Tomislav Dragovich, MD, PhD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Answer

Biologic agents used in the treatment of colon cancer include monoclonal antibodies against vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR), as well as a kinase inhibitor and a decoy receptor for VEGF. Such agents include the following:

  • Bevacizumab (Avastin, Mvasi)
  • Cetuximab (Erbitux)
  • Nivolumab (Opdivo)
  • Panitumumab (Vectibix)
  • Pembrolizumab (Keytruda)
  • Regorafenib (Stivarga)
  • Ziv-aflibercept (Zaltrap)
  • Larotrectinib (Vitrakvi)

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