How is adjuvant therapy used to treat colon cancer in elderly patients?

Updated: Apr 15, 2020
  • Author: Tomislav Dragovich, MD, PhD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Answer

In an observational study of 1291 patients with stage III colon cancer, 56% of whom received adjuvant chemotherapy, van Erning et al concluded that adjuvant chemotherapy should be considered in elderly patients with stage III disease. Adjuvant chemotherapy reduced the risk of distant recurrence after surgery by about half in both elderly patients and younger ones. With adjuvant chemotherapy, hazard ratios for distant recurrence were 0.50 in patients < 75 years of age and 0.57 in those 75 years and older. [91, 91]


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