How does the prognosis of colon cancer vary by stage?

Updated: Apr 15, 2020
  • Author: Tomislav Dragovich, MD, PhD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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A review of Surveillance, Epidemiology, and End Results (SEER) population-based data on colon cancer by the American Joint Committee on Cancer (AJCC) Hindgut Taskforce found the following:

  • T1-2N2 cancers have a better prognosis than T3-4N2 cancers

  • T4bN1 and T4N2 cancers have a similar prognosis

  • T1-2N1, T2N0, and T3N0 cancers have a similar prognosis

  • T1-2N2a, T2N0, T3N0 (T1N2a), and T4aN0 (T2N2a) have a similar prognosis

  • Prognosis for T4a lesions is better than that of T4b by N category

  • The number of positive nodes affects prognosis

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