Which molecular prognostic factors are not yet incorporated into standard clinical practice for colon cancer?

Updated: Apr 15, 2020
  • Author: Tomislav Dragovich, MD, PhD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Answer

Molecular prognostic factors that have been investigated but not incorporated into standard clinical practice include the following:

  • p53

  • Loss of heterozygosity for 18q [67]

  • Mutations of deleted in colon cancer gene (DCC)

  • Epidermal growth factor receptor (EGFR) gene amplification


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