What are the prognostic factors associated with staging of colon cancer?

Updated: Apr 15, 2020
  • Author: Tomislav Dragovich, MD, PhD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Answer

Patient prognosis is a function of the clinical and histopathologic stage of colon cancer at diagnosis. In addition to the well-established significance of standard pathologic features such as depth of bowel wall penetration (T), number of locoregional lymph nodes involved (N), and presence of extra-colonic metastases (M), several other factors have been proved to be of importance. These include number of harvested and processed lymph nodes, histologic grade, and evidence of lymphovascular and perineural invasion.


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