Why is colonoscopy colon cancer screening contraindicated in patients on clopidogrel therapy?

Updated: Apr 15, 2020
  • Author: Tomislav Dragovich, MD, PhD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Answer

Patients on clopidogrel therapy are at significantly higher risk for delayed but not immediate bleeding when they have polyps removed during colonoscopy. [56, 57] Because interruption of clopidogrel therapy in patients with coronary artery disease increases the risk of serious ischemic events, elective colonoscopy and polypectomy should be delayed in these patients until cessation of clopidogrel therapy is considered safe. [56, 57]


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