What are the staging classifications for distal bile duct tumors in cholangiocarcinoma (CCC)?

Updated: Dec 28, 2019
  • Author: Peter E Darwin, MD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Answer

Table 3.  TNM staging for distal bile duct tumors. (Open Table in a new window)

T - Primary tumor

TX

Primary tumor cannot be assessed

T0

No evidence of primary tumor

Tis

Carcinoma in situ – high-grade dysplasia

T1

Tumor invades the bile duct wall with a depth less than 5 m

T2

Tumor invades the bile duct wall with a depth of 5–12 m

T3

Tumor invades the bile duct wall with a depth greater than 12 mm

T4

Tumor involves the celiac axis, superior mesenteric artery, and/or common hepatic artery

N – Regional lymph nodes

NX

Regional lymph nodes cannot be assessed

N0

No regional lymph node metastasis

N1

Metastasis in 1-3 regional lymph nodes

N2

Metastasis in ≥4 regional lymph nodes

M – Distant metastasis

M0

No distant metastasis

M1

Distant metastasis