What are the staging classifications for intrahepatic bile duct tumors in cholangiocarcinoma (CCC)?

Updated: Dec 28, 2019
  • Author: Peter E Darwin, MD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Answer

Table 1. TNM staging for intrahepatic bile duct tumors (Open Table in a new window)

T - Primary tumor

TX

Primary tumor cannot be assessed

T0

No evidence of primary tumor

Tis

Carcinoma in situ (intraductal tumor)

T1

Solitary tumor without vascular invasion, ≤5 cm or > 5 cm

 

T1a

Solitary tumor ≤5 cm without vascular invasion

 

T1b

Solitary tumor > 5 cm without vascular invasion

T2

Solitary tumor with intrahepatic vascular invasion, or multiple tumors with or without vascular invasion

T3

Tumor perforating the visceral peritoneum

T4

Tumor involving local extrahepatic structures by direct invasion

N – Regional lymph nodes

NX

Regional lymph nodes cannot be assessed

N0

No regional lymph node metastasis

N1

Regional lymph node metastasis present

M – Distant metastasis

M0

No distant metastasis

M1

Distant metastasis present