How does the incidence of cholangiocarcinoma (CCC) vary by sex and age?

Updated: Dec 28, 2019
  • Author: Peter E Darwin, MD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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In both males and females, cholangiocarcinoma is most common in persons in their 60s and 70s. The male-to-female ratio for cholangiocarcinoma is 1:2.5 in patients in their 60s and 70s and 1:15 in patients younger than 40 years. According to the American Cancer Society, the number of new cases of liver and intrahepatic bile duct cancer in 2019 is estimated to be 29,480 for men and 12,550 for women, with deaths estimated at 21,600 and 10,180, respectively. The estimated number of new cases of gallbladder and other biliary cancers (extrahepatic cholangiocarcinoma) are 5,810 for men and 6,550 for women, with estimated deaths of 1,610 and 2,350, respectively.12Cancer Fa

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