What is the role of surgery in the treatment of soft-tissue angiosarcoma (AS)?

Updated: Sep 04, 2018
  • Author: Maria Belén Carsi, MD, PhD, FRCS; Chief Editor: Edwin Choy, MD, PhD  more...
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Surgical treatment of angiosarcoma of the soft tissue, retroperitoneum, and abdomen is as follows [6] :

  • Target obtaining wide surgical margins, with at least 2 cm of unaffected tissue surrounding the tumor. The resection should include skin when applicable and the soft tissue around the angiosarcoma. Resect biopsy sites, including the biopsy tract, en bloc with the specimen.

  • Resection of large lesions can be extremely difficult and sometimes requires amputation for local control; however, local control does not prevent distant relapse.

  • Free surgical margins sometimes have anatomic constraints, especially in retroperitoneal tumors.

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