How is cutaneous angiosarcoma (AS) treated?

Updated: Sep 04, 2018
  • Author: Maria Belén Carsi, MD, PhD, FRCS; Chief Editor: Edwin Choy, MD, PhD  more...
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Answer

The best outcomes are reported with surgery followed by radiotherapy. The role of chemotherapy in cutaneous angiosarcoma has not yet been established, although for patients with metastasis or tumors deemed unresectable, doxorubicin (intraarterial or systemic) is indicated. [23]

Paclitaxel as a single agent has shown substantial activity against angiosarcoma of the scalp or face, even in patients previously treated with chemotherapy or radiation therapy. [27] Further investigation is warranted to define the optimal treatment dose and schedule.


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