What causes angiosarcoma (AS)?

Updated: Sep 04, 2018
  • Author: Maria Belén Carsi, MD, PhD, FRCS; Chief Editor: Edwin Choy, MD, PhD  more...
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Answer

The etiology of most cases of angiosarcoma is unknown. The tumors may develop as a complication of a preexisting condition. The following factors may be associated with tumor development [14, 11] :

  • Radical mastectomy
  • Radiotherapy
  • Foreign materials
  • Environmental carcinogens
  • Preexisting benign lesions (eg, bone infarct, pagetoid bone, chronic osteomyelitis)

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