Which medications in the drug class Aldosterone Antagonists, Selective are used in the treatment of Androgen Excess?

Updated: Mar 14, 2018
  • Author: Mohamed Yahya Abdel-Rahman, MD, MSc; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Answer

Aldosterone Antagonists, Selective

Aldosterone antagonists may reduce free testosterone levels and compete with androgens binding at receptor sites.

Spironolactone (Aldactone)

Aldosterone antagonist that competes with testosterone and dihydrotestosterone receptor sites. It also reduces free testosterone levels as more is bound by the increased quantity of SHBG. Used most effectively in combination with an OC.


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