When is a synthetic ACTH (corticotropin) stimulation test indicated in the evaluation of androgen excess?

Updated: Mar 14, 2018
  • Author: Mohamed Yahya Abdel-Rahman, MD, MSc; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Answer

The corticotrophin stimulation test is a diagnostic test for nonclassic congenital adrenal hyperplasia when levels of 17-hydroxyprogesterone are < 200 ng/dL (6.05 nmol/L). [69] For this test, 17-hydroxyprogesterone is measured 1 hour after injection of synthetic corticotrophin. levels >10 ng/dL (30.02 nmol/L) are diagnostic for nonclassic adrenal hyperplasia.


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