What is the role of dehydroepiandrosterone sulphate (DHEAS) measurement in the evaluation of androgen excess?

Updated: Mar 14, 2018
  • Author: Mohamed Yahya Abdel-Rahman, MD, MSc; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Answer

DHEAS is secreted exclusively by the adrenal glands and is therefore a good marker for adrenal androgen production. A mildly elevated DHEAS level is common in women with PCOS. [67] In contrast, DHEAS values above 700 ng/dL (7µg/ml, 18umol/L) are suggestive of adrenal neoplasm. [68]


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