Which medications are used in the treatment of endometriosis?

Updated: May 10, 2021
  • Author: G Willy Davila, MD; Chief Editor: Michel E Rivlin, MD  more...
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Answer

Medical therapy for treating endometriosis involves hormonal therapy. Progestins, combination estrogens/progestins, danazol, and gonadotropin-releasing hormone (GnRH) antagonists (eg, elagolix), or GnRH agonists with or without hormone replacement therapy are some of the medications used. Patients should not begin a regimen of danazol or GnRH agonists unless they are monitored by a gynecologist and have a laparoscopically confirmed diagnosis of endometriosis. Evidence for the use of aromatase inhibitors is currently limited.

Suppression of ovulation and menses often occurs with medical management.


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