How does the degree of pain correlate with the severity of endometriosis?

Updated: May 10, 2021
  • Author: G Willy Davila, MD; Chief Editor: Michel E Rivlin, MD  more...
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Although a significant number of women with endometriosis remain asymptomatic (approximately one third), [1] the most important point to remember is that the degree of visible endometriosis has no correlation with the degree of pain or other symptomatic impairment, because the location and depth of endometrial implants affect the symptomatology. [42] However, pain does correlate with the depth of tissue infiltration, as pain is thought to be related to the degree of peritoneal inflammation rather than the volume of implants. [43, 44] Associated intrapelvic/intra-abdominal adhesions are also important determinants of the degree of pain experienced. Midline disease is generally believed to be more painful than lateral disease. In addition to pain, patients present with nonspecific symptoms of fatigue, generalized malaise, and sleep disturbances.

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