How is atrophic vaginitis treated?

Updated: Dec 04, 2018
  • Author: Hetal B Gor, MD, FACOG; Chief Editor: Michel E Rivlin, MD  more...
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Answer

Atrophic vaginitis can be treated with lubricants, estrogen vaginal cream, tablets, and rings, among others. A study by Shen et al indicated that low-dose estrogen therapy in atrophic vaginitis causes a rise in the proportion of Lactobacillus species in the vaginal microbiome while reducing the proportion of Gardnerella. In addition, serum estradiol levels rose four-fold in the study, vaginal pH was reduced, and the vaginal maturation index almost doubled. [14]

Vaginal suppositories containing human Lactobacillus strains are under investigation, as are changes in formulation strategies to improve pharmacologic delivery and treatment modalities. [15]


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