What is the role of a vaginal swab molecular-based test in the workup of vaginitis?

Updated: Dec 04, 2018
  • Author: Hetal B Gor, MD, FACOG; Chief Editor: Michel E Rivlin, MD  more...
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A cross-sectional study that involved 1,740 patients with vaginitis symptoms by Gaydos et al reported that a vaginal swab molecular-based test collected by patients by themselves or by clinicians can accurately diagnose most common bacterial, fungal, and protozoan causes of vaginitis. The vaginal swab test sensitivity for bacterial vaginosis was 90.5% (95% confidence interval [CI] 88.3-92.2%) and specificity was 85.8% (95% CI 83.0-88.3%). For Candida, the test sensitivity was 90.9% (95% CI 88.1-93.1%) and specificity was 94.1% (95% CI 92.6-95.4%) and test sensitivity was 93.1% (95% CI 87.4-96.3%) and specificity was 99.3% (95% CI 98.7-99.6%) for trichomoniasis. [9]

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