What is the prognosis of struma ovarii?

Updated: Mar 08, 2019
  • Author: Lisa Rubinsak, MD; Chief Editor: Michel E Rivlin, MD  more...
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Answer

For the vast majority of patients, the struma is benign, and the prognosis is excellent. Even in malignant cases, adjuvant iodine-131 ablation with surgical extirpation has proven curative. Recurrences may be detected using iodine-123 scanning, and repeat iodine radioablation can lead to extended disease-free survival.

In an analysis of 88 patients with malignant struma ovarii, several factors were identified as being associated with recurrence or extraovarian spread. These include adhesions, peritoneal fluid of 1 liter or more, ovarian serosal rent, a papillary histology, or a struma component 12 cm or more. The overall survival rate for all patients is 89% at 10 years and 84% at 25 years. [17]


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