What is the risk for endometrial hyperplasia and carcinoma in patients with polycystic ovarian syndrome (PCOS)?

Updated: Sep 19, 2019
  • Author: Richard Scott Lucidi, MD, FACOG; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
  • Print

Patients with PCOS are also at an increased risk for endometrial hyperplasia and carcinoma. [5, 38] The chronic anovulation in PCOS leads to constant endometrial stimulation with estrogen without progesterone, and this increases the risk of endometrial hyperplasia and carcinoma. The Royal College of Obstetricians and Gynaecologists (RCOG) recommends induction of withdrawal bleeding with progestogens a minimum of every 3-4 months. [5]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!