What is the role of lab studies in the evaluation of endometritis?

Updated: Apr 25, 2019
  • Author: Michel E Rivlin, MD; Chief Editor: Michel E Rivlin, MD  more...
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Although the diagnosis of endometritis is principally made on clinical grounds, laboratory studies can be helpful for supporting the diagnosis and excluding or identifying other diagnostic possibilities.

The 2010 and 2015 CDC guidelines on sexually transmitted diseases treatment agree that cervicitis can be a sign of endometritis and that women who are experiencing a new episode of cervicitis should be tested for endometritis, as well as other PID, gonorrhea, and chlamydia. [1, 2]

Endometrial biopsy can be obtained to assess chronic endometritis in the nonobstetric population. Chronic endometritis is associated with abnormal bleeding, recurrent abortion, and infertility. It is a subtle condition and is therefore difficult to diagnose. The diagnosis is ultimately based on the presence of plasma cells in the endometrial stroma upon histopathological examination. [15]

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