What is the role of CBC count in the diagnosis of eclampsia?

Updated: Apr 18, 2019
  • Author: Michael G Ross, MD, MPH; Chief Editor: Ronald M Ramus, MD  more...
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Answer

Answer

A complete blood cell (CBC) count may reveal the following:

  • Anemia due to microangiopathic hemolysis, hemoconcentration due to third spacing, or physiologic hemodilution of pregnancy

  • Peripheral smear (schistocytes, burr cells, echinocytes)

  • Increased bilirubin (>1.2 mg/dL)

  • Thrombocytopenia (< 100,000) due to hemolysis and low platelet count associated with HELLP syndrome (seen in 20-25% of patients with eclampsia) [4]

  • Low serum haptoglobin levels

  • Elevated lactate dehydrogenase (LDH) levels (threshold of 180–600 U/L)


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