How is CNS pathology of eclampsia evaluated?

Updated: Apr 18, 2019
  • Author: Michael G Ross, MD, MPH; Chief Editor: Ronald M Ramus, MD  more...
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Seizures in the first trimester or well into the postpartum period probably are due to CNS pathology and warrant full evaluation, including computed tomography (CT) scanning of the head, lumbar puncture (if clinical evidence of meningitis or concern for hemorrhage exists), determination of electrolyte levels, and urine or serum toxicologic screening. Do not overlook other neurologic causes of seizure, particularly if the seizure occurs more than 24 hours after delivery. In addition, rule out hypoglycemia as cause of seizure or result of seizure, and rule out hyperglycemia as a cause of mental status changes.

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