What are the factors associated with endothelial dysfunction in eclampsia?

Updated: Apr 18, 2019
  • Author: Michael G Ross, MD, MPH; Chief Editor: Ronald M Ramus, MD  more...
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Answer

Answer

Factors associated with endothelial dysfunction have been shown to be increased in the systemic circulation of women suffering from eclampsia. These include the following [1] :

  • Cellular fibronectin

  • Von Willebrand factor

  • Cell adhesion molecules (ie, P-selectin, vascular endothelial adhesion molecule-1 [VCAM-1]

  • Intercellular adhesion molecule-1 [ICAM-1])

  • Cytokines (ie, interleukin-6 [IL-6])

  • Tumor necrosis factor-α [TNF-α]


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