What is the role of lab testing in the evaluation of secondary dysmenorrhea?

Updated: Sep 23, 2019
  • Author: Karim Anton Calis, PharmD, MPH, FASHP, FCCP; Chief Editor: Michel E Rivlin, MD  more...
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The following laboratory studies may be performed to identify or exclude organic causes of secondary dysmenorrhea:

  • Complete blood count (CBC) with differential to search for evidence of infection or a neoplastic process

  • Gonococcal and chlamydial cultures, enzyme immunoassay (EIA), and DNA probe testing to exclude sexually transmitted infections (STIs) and pelvic inflammatory disease (PID)

  • Quantitative human chorionic gonadotropin level to exclude ectopic pregnancy

  • Erythrocyte sedimentation rate (ESR) for subacute salpingitis

  • Urinalysis to exclude urinary tract infection

  • Stool guaiac to rule out GI bleeding

  • Cancer antigen 125 (CA-125) assay – This test has relatively low negative predictive value and thus is of limited clinical utility for evaluating dysmenorrheal women

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