What are the guidelines for treating metastatic cervical cancer?

Updated: Feb 12, 2019
  • Author: Cecelia H Boardman, MD; Chief Editor: Warner K Huh, MD  more...
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Answer

The NCCN and ESMO recommend cisplatin-based chemotherapy on a palliative basis. [8, 108] The NCCN further recommends that radiation therapy may be considered for control of bleeding and pain. In addition, for second-line therapy, docetaxel, gemcitabine, ifosfamide, 5-fluorouracil, mitomycin, irinotecan, and topotecan may be considered (category 2B recommendation), as well as pemetrexed and vinorelbine (category 3 recommendation). Bevacizumab as single-agent therapy is also acceptable. [8]


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