What is the role of MRI in the evaluation of amenorrhea?

Updated: Oct 14, 2019
  • Author: Kristi A Tough DeSapri, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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MRI of the pituitary and hypothalamus is often indicated in the evaluation of amenorrhea. Request imaging of the hypothalamic/pituitary area specifically, rather than a study of the entire brain. This achieves higher resolution. MRI is indicated in the following circumstances:

  • Associated headaches or visual-field cuts

  • Profound estrogen deficiency with otherwise unexplained amenorrhea

  • Hyperprolactinemia

  • Elevated gonadotropins in the setting of markedly elevated serum estradiol level

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