What is the role of zinc in the treatment of COVID-19?

Updated: Jan 12, 2021
  • Author: Setu K Patolia, MD, MPH; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Answer

Zinc is an essential micronutrient factoring in anti-inflammatory and antioxidant functions. In vitro, zinc deficiency is related to enhanced IL-6 and IL-1β production, thereby translating to a pronounced inflammatory response. Hence, there are various ongoing studies to evaluate the role of zinc in antiviral immunity. The recommended dietary allowance for zinc is 11 mg/day in men and 8 mg/day in women. There are concerns for impaired intestinal absorption of copper and suppression of the immune system with long-term intake of high-dose zinc. [57]


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