What are the ASCO/IDSA guidelines for inpatient treatment of neutropenic cancer patients?

Updated: Sep 16, 2018
  • Author: Alexandre Chan, PharmD, MPH, FCCP, BCPS (AQ-ID), BCOP; more...
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Answer

Answer

Patients who are undergoing outpatient management should be evaluated for admission to the hospital if any of the following occur:

  • Failure to defervesce after 2 to 3 days of an initial, empirical, broad-spectrum antibiotic regimen
  • Fever recurrence after a period of defervescence
  • New signs or symptoms of infection
  • Use of oral medications is no longer possible or tolerable
  • Change in the empirical regimen or an additional antimicrobial drug becomes necessary
  • Microbiologic tests identify species not susceptible to the initial regimen

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