What are the CDC guidelines on Zika infection testing during pregnancy?

Updated: Jun 30, 2021
  • Author: Bhagyashri D Navalkele, MD, MBBS; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Guidelines on Zika testing in pregnancy by the Centers for Disease Control and Prevention are as follows [48] :​

Asymptomatic pregnant women:

  • For asymptomatic pregnant persons living in or with recent travel to the United States and its territories, routine Zika virus testing is NOT currently recommended.
  • For asymptomatic pregnant women with recent travel to  an area with risk for Zika outside the United States and its territories, Zika virus testing is NOT routinely recommended, but NAAT testing may still be considered up to 12 weeks after travel.
  • Zika virus serologic testing is NOT recommended for asymptomatic pregnant women.

Symptomatic pregnant women:

  • For symptomatic pregnant women who had recent travel to areas with  a risk of Zika, specimens should be collected for Zika virus NAAT testing on a serum specimen, and Zika virus NAAT on a urine specimenas soon as possible after the onset of symptoms up to 12 weeks after symptom onset. 
  • Zika virus IgM testing is NOT recommended for symptomatic pregnant women.
  • For symptomatic pregnant women who have had sex with someone who lives in or recently traveled to areas with  a risk for Zika, specimen for Zika NAAT should be collected as soon as possible after the onset of symptoms up to 12 weeks after symptom onset.

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