What are the CDC guidelines on Zika infection testing during pregnancy?

Updated: Dec 11, 2018
  • Author: Bhagyashri D Navalkele, MD, MBBS; Chief Editor: Michael Stuart Bronze, MD  more...
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Guidelines on Zika testing in pregnancy by the Centers for Disease Control and Prevention are as follows: [35, 36]

  • Screen pregnant women for risk of Zika virus exposure and symptoms of Zika virus infection. Promptly test pregnant women with Zika virus nucleic acid test (NAT) if they become symptomatic during their pregnancy or if a sexual partner tests positive for Zika virus infection.
  • Consider NAT testing at least once per trimester, unless a previous test has been positive.
  • Consider NAT testing of amniocentesis specimens if amniocentesis is performed for other reasons.
  • Counsel pregnant women each trimester on the limitations of IgM and NAT testing.
  • Consider IgM testing to determine baseline Zika virus IgM levels as part of preconception counseling.

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