Which imaging studies are indicated in the workup of Zika virus infection in pregnancy?

Updated: Dec 11, 2018
  • Author: Bhagyashri D Navalkele, MD, MBBS; Chief Editor: Michael Stuart Bronze, MD  more...
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All pregnant women with a history of travel to an area of active Zika virus infection should undergo fetal ultrasonography to evaluate for microcephaly or intracranial calcifications. [21] Detection of a fetal anomaly should be followed by amniocentesis for evaluation of intrauterine Zika virus infection. The sensitivity and specificity of amniocentesis for determination of congenital infection and prediction of fetal abnormality is unknown. [21]

The WHO recommends that newborns with severe microcephaly (more than 3 standard deviations below the mean) undergo neuroimaging. [18]

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