Which lab testing for Zika virus infection is indicated in pregnancy?

Updated: Jun 30, 2021
  • Author: Bhagyashri D Navalkele, MD, MBBS; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Pregnant women with symptoms and possible exposure to Zika virus should undergo molecular and serological diagnostic testing for confirmation of Zika virus infection. A NAAT on serum and urine specimen and IgM antibody test on serum should be performed and collected within 12 weeks of symptom onset. Below diagnostic testing algorithm should be used to interpret diagnosis of Zika and distinguish from dengue virus infection.

Testing algorithm for pregnant women with a clinically compatible illness and risk for Zika and Dengue virus. Courtesy of the Centers for Disease Control and Prevention (CDC).

Testing algorithm for pregnant women with a clinic Testing algorithm for pregnant women with a clinically compatible illness and risk for Zika and Dengue virus. Courtesy of the Centers for Disease Control and Prevention (CDC).

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