Which hosts are susceptible to Zika virus?

Updated: Dec 11, 2018
  • Author: Bhagyashri D Navalkele, MD, MBBS; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print
Answer

Zika virus is well-adapted to grow in various hosts, ranging from arthropods to vertebrates. Viral attachment to unidentified cellular receptors is mediated by the E (envelope) glycoprotein. This is followed by endocytic uptake and then uncoating of the nucleocapsid and release of viral RNA into the cytoplasm. A viral polyprotein is produced and modified by the endoplasmic reticulum. Immature virions collect both in the endoplasmic reticulum and in secretory vesicles before being released. [1]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!