What are the ASCO treatment guidelines for chemotherapy-induced peripheral neuropathy (CIPN)?

Updated: Nov 04, 2020
  • Author: Alexandre Chan, PharmD, MPH, FCCP, BCPS (AQ-ID), BCOP; more...
  • Print
Answer

Answer

The ASCO guidelines recommend duloxetine to treat painful CIPN. The guidelines advise that outside the context of a clinical trial, no recommendations can be made on the use of the following for the treatment of CIPN:

  • Exercise therapy
  • Acupuncture
  • Scrambler therapy
  • Gabapentin/pregabalin
  • Topical gel treatment containing baclofen, amitriptyline HCL, plus/minus ketamine
  • Tricyclic antidepressants
  • Oral cannabinoids

ASCO notes that although preliminary evidence suggests that exercise, acupuncture, and scrambler therapy offer potential benefit, larger sample-sized definitive studies are needed to confirm efficacy and clarify risks.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!