What are the ESMO treatment guidelines for metastatic soft tissue sarcoma (STS) of the extremities, superficial trunk, or head and neck?

Updated: Sep 02, 2018
  • Author: Steven C Katz, MD, FACS; Chief Editor: Edwin Choy, MD, PhD  more...
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Answer

Answer

ESMO recommendations for treatment of metastatic disease include the following: [6]

  • Chemotherapy may be offered for synchronous lung metastases, in the absence of extrapulmonary disease.
  • Surgery is an option for completely resectable residual lung metastases following chemotherapy, especially when a tumor response is achieved.
  • For extrapulmonary metastatic disease, chemotherapy is the treatment of choice.
  • Radiation therapy may be used with palliative intent.
  • Best supportive care alone is acceptable, especially if second-line therapies have been given previously.
  • Enrollment in clinical trials is recommended.

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