What are the ESMO treatment guidelines for stage II-III soft tissue sarcoma (STS) of the extremities, superficial trunk, or head and neck?

Updated: Sep 02, 2018
  • Author: Steven C Katz, MD, FACS; Chief Editor: Edwin Choy, MD, PhD  more...
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The ESMO guidelines differ from NCCN in that they do not recommend adjuvant chemotherapy as a standard treatment option for stage II or III STS. [6]  Chemotherapy options for individual high-risk patients with local/locoregional disease include the following:

  • Adjuvant chemotherapy
  • Neoadjuvant chemotherapy with anthracyclines plus ifosfamide for at least three cycles

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