What are the ESMO-PaedCan-EURACAN guidelines on the diagnosis of bone sarcoma?

Updated: Jul 01, 2020
  • Author: Mrinal M Gounder, MD; Chief Editor: Edwin Choy, MD, PhD  more...
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Joint guidelines from the European Society for Medical Oncology, European Reference Network for Paediatric Cancers, and European network for Rare adult solid Cancer (ESMO-PaedCan-EURACAN) recommend conventional radiography in two planes as the first radiological investigation. When malignancy cannot be excluded with certainty on radiographs, the next step should be magnetic resonance imaging (MRI) of the whole compartment with adjacent joints. CT scan may provide additional information by allowing a better visualisation of calcifications, periosteal bone formation, and cortical destruction. [2]

Both guidelines agree that biopsy is required to confirm the diagnosis prior to any surgical procedure and should be performed at a specialized center that will provide the definitive treatment. [1, 2]

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