What are the guidelines on the treatment of pancreatic insulinomas?

Updated: Dec 23, 2018
  • Author: Evan S Ong, MD, MS; more...
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Recommendations for insulinoma treatment include the following:

  • Stabilize glucose levels with diet and/or diazoxide; everolimus may be considered

  • Primary treatment is enucleation; consider laparoscopic resection for solitary tumors

  • Deeper or invasive tumors or those close to the main pancreatic duct require pancreatoduodenectomy if located in the head and laparoscopic distal pancreatectomy if in a distal location, with preservation of the spleen for smaller tumors

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