What are the ENETS guidelines on the treatment of neuroendocrine tumors (NETs) of the appendix?

Updated: Dec 23, 2018
  • Author: Evan S Ong, MD, MS; more...
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Answer

Answer

The 2016 ENETS revised guidelines recommendations include the following [18] :

  • Tumors ≤2 cm: Simple appendicectomy unless incompletely resected
  • Tumors >2 cm: Right hemicolectomy with node dissection

In rare cases, right hemicolectomy with node dissection may be indicated for appendiceal tumors measuring 1–2 cm. This exception applies only to tumors with one or more of the following [18] :

  • Positive or unclear margins or with deep mesoappendiceal invasion (ENETS T2)
  • Higher proliferation rate (G2)
  • Vascular invasion

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