What are the ENETS guidelines on the treatment of gastric neuroendocrine tumors (NETs)?

Updated: Dec 23, 2018
  • Author: Evan S Ong, MD, MS; more...
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Answer

Answer

The 2016 revised ENETS guidelines prefer conservative management strategies over surgery for type I tumors. The guidelines recommend resection of tumors ≥10 mm performed by endoscopists experienced in gastric tumors, using either endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD). [15]

For type II tumors, local or limited excision can be recommended, but this should be patient tailored at multidisciplinary NET centers of excellence.Type III tumors should be treated similarly to gastric adenocarcinoma with surgery (partial or total gastrectomy with lymph node dissection). Systemic therapy is required for inoperable or stage 4 disease. [15]


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