What are the ESMO guidelines for surveillance of attenuated familial adenomatous polyposis (FAP)?

Updated: Mar 18, 2021
  • Author: Elwyn C Cabebe, MD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
  • Print


Attenuated FAP

  • Colon and rectum: Colonoscopy every 1 to 2 years, starting at age 18 to 20 years and continued lifelong in mutation carriers. Once adenomas are detected, colonoscopy should be carried out annually.

  • Gastroduodenal adenomas: Gastroduodenal endoscopy starting when colorectal polyposis is diagnosed or at age 25 to 30 years, whichever comes first. Surveillance intervals are based on the Spigelman stage.

  • Thyroid cancer: Annual cervical ultrasonography may be considered starting at age 25 to 30 years.

  • Desmoid tumors: A baseline CT scan or MRI should be considered if risk factors (positive family history for desmoids and site of the mutation in APC).

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!