What are the NCCN criteria for average risk individuals for colorectal cancer screening?

Updated: Mar 18, 2021
  • Author: Elwyn C Cabebe, MD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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The National Comprehensive Cancer Network (NCCN) has released separate guidelines for average-risk and high-risk individuals. [8, 9] For average individuals, the recommendations are nearly identical to those of the joint American Cancer Society (ACS), US Multi-Society Task Force on Colorectal Cancer, and American College of Radiology.

The NCCN criteria for average risk are as follows [8]

  • Age ≥50 y
  • No history of adenoma, sessile serrated polyp, or colorectal cancer
  • No history of inflammatory bowel disease
  • Negative family history for colorectal cancer or confirmed advanced adenoma (ie, high-grade dysplasia, ≥1 cm, villous or tubulovillous histology) or an advanced sessile serrated polyp (≥1 cm, any dysplasia)

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