What are alternative imaging studies for patients with risk factors for contrast-induced nephropathy (CIN)?

Updated: Dec 18, 2018
  • Author: Anita Basu, MD, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
  • Print
Answer

In patients with risk factors for CIN, the possibility of alternative imaging studies that do not need contrast should be explored. MRI with gadolinium is no longer considered a safe alternative to iodinated contrast because of the risk of nephrogenic systemic fibrosis (NSF), an irreversible, debilitating condition seen mostly in patients with an eGFR of less than 30 mL/min/1.73 m2. Of gadolinium-based contrast agents, gadoteridol and gadobenate dimeglumine are considered to pose the lowest risk of NSF; no association of either agent with an unconfounded case of NSF has yet to be established. [59]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!