What are the mortality rates for contrast-induced nephropathy (CIN)?

Updated: Dec 18, 2018
  • Author: Anita Basu, MD, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Patients who require dialysis have a considerably worse prognosis, with a reported rate of 35.7% inhospital mortality (compared with 7.1% in the nondialysis group) and a 2-year survival rate of only 19%.

CIN by itself may be an independent mortality risk factor. Following invasive cardiology procedures, patients with normal baseline renal function who develop CIN have reduced survival compared with patients with baseline chronic CKD who do not develop CIN.

In one study of the effect of CIN on long-term mortality after percutaneous coronary intervention in patients with or without CKD, CIN was found to be significantly correlated with long-term mortality in the entire cohort (hazard ratio [HR] 2.26, 95% confidence interval [CI] 1.62 to 2.29, P< 0.0001) and in patients with CKD (HR 2.62, 95% CI 1.91 to 3.57, P< 0.0001) but not in patients without CKD (HR 1.23, 95% CI 0.47 to 2.62, P = 0.6). The rate of CIN in patients with CKD was 11% and 2% in patients without CKD. [25]


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