Which findings help differentiate cerebral salt wasting (CSW) from syndrome of inappropriate antidiuretic hormone secretion (SIADH)?

Updated: Aug 16, 2019
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
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The differences and similarities in findings for CSW and SIADH are itemized as follows:

  • Hyponatremia - Present in both CSW and SIADH

  • Urine Na - Increased in both CSW and SIADH

  • Volume - Reduced in CSW and normal or increased in SIADH

  • Salt wasting - Gross in CSW and self-limited in SIADH

  • Urine output - Polyuria in CSW and variable in SIADH

  • Hypouricemia - Occasional in CSW and frequent in SIADH

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