What are treatment options for chronic asymptomatic syndrome of inappropriate antidiuretic hormone secretion (SIADH)?

Updated: Aug 16, 2019
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

In a chronic asymptomatic setting, the principal options are as follows:

  • Fluid restriction

  • Vassopressin-2 receptor antagonists

  • If vasopressin-2 receptor antagonists are unavailable or if local experience with them is limited, other agents to be considered include loop diuretics with increased salt intake, urea, mannitol, and demeclocycline

See Treatment and Medication for more detail.


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